The North West Tasmania region covers a vast area including the towns of Devonport, Burnie, Strahan and Queenstown as well as Cradle Mountain National Park. The gateway to this region is Devonport, with an airport and the Spirit of Tasmania (ferry between Victoria and Tasmania) terminus. The port handles much of the export produce from the rich agricultural areas around Devonport. The town itself is used as an arrival or departure port for most travellers rather than a destination itself.

A major farming area stretches from Devonport along the coast to Stanley. Many of Australia's finest vegetable and dairy produce come from this region. Stanley is an historic fishing village with a large volcanic headland - The Nut - accessible by chairlift. Far out to the north-west in the stormy waters of Bass Strait, King Island consists very much of uninhabited bushland teeming with wildlife. The island produces some of the best dairy products, for which it is famous.

Cradle Mountain-Lake St Clair National Park, in Tasmania's World Heritage Wilderness Area, offers a rugged environment with many wilderness retreats and walking tracks. Icy streams, ancient pines, glacial lakes and wildlife surround the jagged contours of Cradle Mountain. The area is one of the most glaciated in Australia and includes Tasmania's highest mountain, Mt Ossa (1617 metres) and Lake St Clair, Australia's deepest natural freshwater lake, the source of the River Derwent.

The West Coast area of Tasmania is made up of rugged coast, mountain ranges, flowing rivers, steep gorges, rainforest wilderness and ghost towns. Strahan is situated on Macquarie Harbour and is the starting point for Gordon River cruises and air tours over the South West Wilderness. Strahan is the only town on this rugged and dangerous coast.